If you need a bit of extra motivation to (start) read(ing) this book, check out Infinite Summer (www.infinitesummer.org). From the site:
The Challenge: Read Infinite Jest over the summer of 2009
You've been meaning to do it for over a decade. Now join endurance bibliophiles from around the web as we tackle and comment upon David Foster Wallace's masterwork, June 21st to September 22nd. A thousand pages ÷ 93 days = 75 pages a week. No sweat.